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Proceedings Paper

Effect of CADe on radiologists’ performance in detection of "difficult" polyps in CT colonography
Author(s): Kenji Suzuki; Masatoshi Hori; Gen Iinuma; Abraham H. Dachman
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Paper Abstract

To investigate the actual usefulness of computer-aided detection (CADe) of polyps as a second reader, we conducted a free-response observer performance study with radiologists in the detection of “difficult” polyps in CT colonography (CTC) from a multicenter clinical trial. The “difficult” polyps were defined as the ones that had been “missed” by radiologists in the clinical trial or rated “difficult” in our retrospective review. Our advanced CADe scheme utilizing massive-training artificial neural networks (MTANNs) technology was sensitive and specific to the “difficult” polyps. Four board-certified abdominal radiologists participated in this observer study. They were instructed, first without and then with our CADe, to indicate the location of polyps and their confidence level regarding the presence of polyps. Our database contains 20 patients with 23 polyps including 14 false-negative (FN) and 7 “difficult” polyps and 10 negative patients. With CADe, the average by-polyp sensitivity of radiologists was improved from 53 to 63% at a statistically significant level (P=0.037). Thus, our CADe scheme utilizing the MTANN technology improved the diagnostic performance of radiologists, including expert readers, in the detection of “difficult” polyps in CTC.

Paper Details

Date Published: 18 March 2013
PDF: 7 pages
Proc. SPIE 8670, Medical Imaging 2013: Computer-Aided Diagnosis, 86700U (18 March 2013); doi: 10.1117/12.2008284
Show Author Affiliations
Kenji Suzuki, Univ. of Chicago (United States)
Masatoshi Hori, Osaka Univ. (Japan)
Gen Iinuma, National Cancer Ctr. (Japan)
Abraham H. Dachman, The Univ. of Chicago (United States)


Published in SPIE Proceedings Vol. 8670:
Medical Imaging 2013: Computer-Aided Diagnosis
Carol L. Novak; Stephen Aylward, Editor(s)

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