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Proceedings Paper

Estimation of the parameters of dye distributions by optical probing
Author(s): Gerd C. Beck; Alwin Kienle; Rudolf W. Steiner
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Paper Abstract

The observable parameters remittance, transmittance and fluorescence emission of layered systems are determined from Monte Carlo simulations and the diffusion approximation. We calculate the effect of additional absorption caused by a fluorescing dye, depending on dye- bearing layer thickness. The results of the simulations are compared to the diffusion approximation, establishing a range of accuracy of the diffusion approximation. We show that, provided the basic optical properties of the system are known, additional absorption and layer thickness can be calculated from non-invasive measurements of remittance and fluorescence emission. We give an estimation of the effect of experimental uncertainty on the results for dye absorption and layer thickness.

Paper Details

Date Published: 31 January 1995
PDF: 11 pages
Proc. SPIE 2326, Photon Transport in Highly Scattering Tissue, (31 January 1995); doi: 10.1117/12.200825
Show Author Affiliations
Gerd C. Beck, Univ. Ulm (Germany)
Alwin Kienle, Univ. Ulm (Germany)
Rudolf W. Steiner, Univ. Ulm (Germany)

Published in SPIE Proceedings Vol. 2326:
Photon Transport in Highly Scattering Tissue
Sigrid Avrillier; Britton Chance; Gerhard J. Mueller; Alexander V. Priezzhev; Valery V. Tuchin, Editor(s)

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