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Proceedings Paper

A novel sensor for high throughput preclinical radiotracer imaging
Author(s): Haris Kudrolli; Harish B. Bhandari; Katherine L. Byrne; Simon R. Cherry; Gregory S. Mitchell; Hamid Sabet; Vivek Nagarkar
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Paper Abstract

Preclinical imaging is a cornerstone of translational research, as all therapeutic drugs need to be tested for efficacy and toxicity on animals prior to human trials. Optical imaging techniques, such as bioluminescence and multispectral fluorescence imaging, currently dominate preclinical functional imaging despite their depth dependent limitations on quantitation and sensitivity. Translating drugs developed with these techniques to clinical models can therefore be difficult. Hence, clinically relevant nuclear imaging techniques, such as SPECT and PET, are therefore becoming increasingly used in preclinical imaging. Dedicated preclinical SPECT and PET systems are now available, but for many preclinical research groups this requires a significant investment in new equipment.

Paper Details

Date Published: 6 March 2013
PDF: 6 pages
Proc. SPIE 8668, Medical Imaging 2013: Physics of Medical Imaging, 866809 (6 March 2013); doi: 10.1117/12.2008165
Show Author Affiliations
Haris Kudrolli, Radiation Monitoring Devices, Inc. (United States)
Harish B. Bhandari, Radiation Monitoring Devices, Inc. (United States)
Katherine L. Byrne, Univ. of California, Davis (United States)
Simon R. Cherry, Univ. of California, Davis (United States)
Gregory S. Mitchell, Univ. of California, Davis (United States)
Hamid Sabet, Radiation Monitoring Devices, Inc. (United States)
Vivek Nagarkar, Radiation Monitoring Devices, Inc. (United States)


Published in SPIE Proceedings Vol. 8668:
Medical Imaging 2013: Physics of Medical Imaging
Robert M. Nishikawa; Bruce R. Whiting; Christoph Hoeschen, Editor(s)

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