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Proceedings Paper

Detecting breast microcalcifications using super-resolution ultrasound imaging: a clinical study
Author(s): Lianjie Huang; Yassin Labyed; Kenneth Hanson; Daniel Sandoval; Jennifer Pohl; Michael Williamson
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Paper Abstract

Imaging breast microcalcifications is crucial for early detection and diagnosis of breast cancer. It is challenging for current clinical ultrasound to image breast microcalcifications. However, new imaging techniques using data acquired with a synthetic-aperture ultrasound system have the potential to significantly improve ultrasound imaging. We recently developed a super-resolution ultrasound imaging method termed the phase-coherent multiple-signal classification (PC-MUSIC). This signal subspace method accounts for the phase response of transducer elements to improve image resolution. In this paper, we investigate the clinical feasibility of our super-resolution ultrasound imaging method for detecting breast microcalcifications. We use our custom-built, real-time synthetic-aperture ultrasound system to acquire breast ultrasound data for 40 patients whose mammograms show the presence of breast microcalcifications. We apply our super-resolution ultrasound imaging method to the patient data, and produce clear images of breast calcifications. Our super-resolution ultrasound PC-MUSIC imaging with synthetic-aperture ultrasound data can provide a new imaging modality for detecting breast microcalcifications in clinic without using ionizing radiation.

Paper Details

Date Published: 29 March 2013
PDF: 10 pages
Proc. SPIE 8675, Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy, 86751O (29 March 2013); doi: 10.1117/12.2007653
Show Author Affiliations
Lianjie Huang, Los Alamos National Lab. (United States)
Yassin Labyed, Los Alamos National Lab. (United States)
Kenneth Hanson, Los Alamos National Lab. (United States)
Daniel Sandoval, The Univ. of New Mexico (United States)
Jennifer Pohl, The Univ. of New Mexico (United States)
Michael Williamson, The Univ. of New Mexico (United States)


Published in SPIE Proceedings Vol. 8675:
Medical Imaging 2013: Ultrasonic Imaging, Tomography, and Therapy
Johan G. Bosch; Marvin M. Doyley, Editor(s)

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