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Proceedings Paper

Sparse-sampling parallel Raman/SERS microspectroscopy for high-throughput molecular analysis of micro and nanoparticles
Author(s): Ji Qi; Wei-Chuan Shih
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Paper Abstract

We present the applications of parallel Raman/SERS microspectroscopy by active illumination for simultaneously obtaining the full Raman/SERS spectra from multiple points within a field of view ~100 x 100 μm2 and ~micron spatial resolution. Two schemes have been employed in these studies: line-scan and programmable active illumination. We demonstrate the rapid classification of microparticles with similar shape, size and refractive index based on their chemical composition. We also demonstrate the rapid microanalysis of self-assembled monolayers on various types of gold nanostructures via SERS.

Paper Details

Date Published: 22 February 2013
PDF: 6 pages
Proc. SPIE 8587, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XI, 85871N (22 February 2013); doi: 10.1117/12.2005718
Show Author Affiliations
Ji Qi, Univ. of Houston (United States)
Wei-Chuan Shih, Univ. of Houston (United States)

Published in SPIE Proceedings Vol. 8587:
Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XI
Daniel L. Farkas; Dan V. Nicolau; Robert C. Leif, Editor(s)

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