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Proceedings Paper

Effective frequency sensitivity of laser speckle contrast measurements
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Paper Abstract

How does speckle contrast K, measured at camera exposures T around 10 ms, give us information about temporal autocorrelation of the speckle pattern with time constants τ < 1 ms, corresponding to Doppler shifts in the KHz range? We explore the implications of this question and show that for any particular assumed temporal speckle autocorrelation function, K measured at T >> τ accurately measures τ, but that K measurements at T < τ are required in order to determine the actual shape of the autocorrelation function. Determining the shape of the autocorrelation function is important if we wish to distinguish between different types of flow or movement in tissue, for example distinguishing Brownian motion or the randomly-oriented flows in capillary networks from more ordered flow in resolvable vessels.

Paper Details

Date Published: 1 March 2013
PDF: 6 pages
Proc. SPIE 8580, Dynamics and Fluctuations in Biomedical Photonics X, 858008 (1 March 2013); doi: 10.1117/12.2005312
Show Author Affiliations
O. B. Thompson, Callaghan Innovation (New Zealand)
Univ. of Auckland (New Zealand)
E. R. Hirst, Callaghan Innovation (New Zealand)
M. K. Andrews, Callaghan Innovation (New Zealand)

Published in SPIE Proceedings Vol. 8580:
Dynamics and Fluctuations in Biomedical Photonics X
Valery V. Tuchin; Donald D. Duncan; Kirill V. Larin; Martin J. Leahy; Ruikang K. Wang, Editor(s)

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