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Proceedings Paper

Blood pulse wave velocity measured by photoacoustic microscopy
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Paper Abstract

Blood pulse wave velocity (PWV) is an important indicator for vascular stiffness. In this letter, we present electrocardiogram-synchronized photoacoustic microscopy for in vivo noninvasive quantification of the PWV in the peripheral vessels of mice. Interestingly, strong correlation between blood flow speed and ECG were clearly observed in arteries but not in veins. PWV is measured by the pulse travel time and the distance between two spot of a chose vessel, where simultaneously recorded electrocardiograms served as references. Statistical analysis shows a linear correlation between the PWV and the vessel diameter, which agrees with known physiology. Keywords: photoacoustic microscopy, photoacoustic spectroscopy, bilirubin, scattering medium.

Paper Details

Date Published: 4 March 2013
PDF: 6 pages
Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85812C (4 March 2013); doi: 10.1117/12.2004232
Show Author Affiliations
Chenghung Yeh, Washington Univ. in St. Louis (United States)
Song Hu, Washington Univ. in St. Louis (United States)
Konstantin Maslov, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)


Published in SPIE Proceedings Vol. 8581:
Photons Plus Ultrasound: Imaging and Sensing 2013
Alexander A. Oraevsky; Lihong V. Wang, Editor(s)

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