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Proceedings Paper

Adaptive optics-assisted optical coherence tomography for imaging of patients with age related macular degeneration
Author(s): Kenta Sudo; Barry Cense
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Paper Abstract

We developed an optical coherence tomography (OCT) prototype with a sample arm that uses a 3.4 mm beam, which is considerably larger than the 1.2 to 1.5 mm beam that is used in commercialized OCT systems. The system is equipped with adaptive optics (AO), and to distinguish it from traditional AO-OCT systems with a larger 6 mm beam we have coined this concept AO-assisted OCT. Compared to commercialized OCT systems, the 3.4 mm aperture combined with AO improves light collection efficiency and imaging lateral resolution. In this paper, the performance of the AOa-OCT system was compared to a standard OCT system and demonstrated for imaging of age-related macular degeneration (AMD). Measurements were performed on the retinas of three human volunteers with healthy eyes and on one eye of a patient diagnosed with AMD. The AO-assisted OCT system imaged retinal structures of healthy human eyes and a patient eye affected by AMD with higher lateral resolution and a 9° by 9° field of view. This combination of a large isoplanatic patch and high lateral resolution can be expected to fill a gap between standard OCT with a 1.2 mm beam and conventional AO-OCT with a 6 mm beam and a 1.5° by 1.5° isoplanatic patch.

Paper Details

Date Published: 26 March 2013
PDF: 7 pages
Proc. SPIE 8567, Ophthalmic Technologies XXIII, 85671W (26 March 2013); doi: 10.1117/12.2004165
Show Author Affiliations
Kenta Sudo, Utsunomiya Univ. (Japan)
Barry Cense, Utsunomiya Univ. (Japan)


Published in SPIE Proceedings Vol. 8567:
Ophthalmic Technologies XXIII
Fabrice Manns; Per G. Söderberg; Arthur Ho, Editor(s)

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