Share Email Print

Proceedings Paper

Stationary microfluidics: molecular diagnostic assays by moving magnetic beads through non-moving liquids
Author(s): Holger Becker; Cornelia Carstens; Dirk Kuhlmeier; Natalia Sandetskaya; Nicole Schröter; Christian Zilch; Claudia Gärtner
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Commonly, microfluidic devices are based on the movement of fluids. For molecular diagnostics assays which often include steps like PCR, this practically always involves a more or less complicated set of external pumps, valves and liquid controls. In the presented paper, we follow a different approach in which the fluid after sample introduction remains stationary and the main bioactive sample molecules are moved through a chain of reaction compartments which contain the different reagents necessary for the assay. The big advantage of this concept is the lack of any external fluid actuation/control. Results on sample carry-over experiments and complete assays will be given.

Paper Details

Date Published: 13 March 2013
PDF: 5 pages
Proc. SPIE 8615, Microfluidics, BioMEMS, and Medical Microsystems XI, 86150B (13 March 2013); doi: 10.1117/12.2004041
Show Author Affiliations
Holger Becker, microfluidic ChipShop GmbH (Germany)
Cornelia Carstens, microfluidic ChipShop GmbH (Germany)
Dirk Kuhlmeier, Fraunhofer-Institut für Zelltherapie und Immunologie (Germany)
Natalia Sandetskaya, Fraunhofer-Institut für Zelltherapie und Immunologie (Germany)
Nicole Schröter, Magna Diagnostics GmbH (Germany)
Christian Zilch, Magna Diagnostics GmbH (Germany)
Claudia Gärtner, microfluidic ChipShop GmbH (Germany)

Published in SPIE Proceedings Vol. 8615:
Microfluidics, BioMEMS, and Medical Microsystems XI
Holger Becker; Bonnie L. Gray, Editor(s)

© SPIE. Terms of Use
Back to Top