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Proceedings Paper

Glucose measurement in interstitial fluid by microdialysis for the calibration of minimally invasive blood glucose monitoring
Author(s): Dachao Li; Ridong Wang; Hao Chong; Yu Liu; Kexin Xu
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Paper Abstract

According to the requirement of the calibration in minimally invasive blood glucose monitoring, a method based on microdialysis was presented to monitor glucose level in interstitial fluid continuously. An experimental system simulating the continuous change of glucose concentration in vivo was built. The influences on recovery of microdialysis caused by flow rate, glucose concentration, and temperature etc. were studied. The results led to the conclusion that the recovery fell by 71.7% when perfusion rate increased from 0.3 μL/min to 3.0 μL/min, while the different concentrations of glucose solutions scarcely contribute to the recovery instead, and the temperatures from 25 to 58 °C caused the recovery to increase by 34.6%.

Paper Details

Date Published: 22 March 2013
PDF: 7 pages
Proc. SPIE 8572, Advanced Biomedical and Clinical Diagnostic Systems XI, 857219 (22 March 2013); doi: 10.1117/12.2003853
Show Author Affiliations
Dachao Li, Tianjin Univ. (China)
Ridong Wang, Tianjin Univ. (China)
Hao Chong, Tianjin Univ. (China)
Yu Liu, Tianjin Univ. (China)
Kexin Xu, Tianjin Univ. (China)

Published in SPIE Proceedings Vol. 8572:
Advanced Biomedical and Clinical Diagnostic Systems XI
Anita Mahadevan-Jansen; Tuan Vo-Dinh; Warren S. Grundfest, Editor(s)

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