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Proceedings Paper

Realistic phantoms for diffuse optical imaging using totally absorbing objects
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Paper Abstract

We propose and validate the design of inhomogeneous phantoms for diffuse optical imaging purposes using totally absorbing objects embedded in a diffusive medium. From Monte Carlo simulations, we show that a given or desired perturbation strength caused by an realistic absorbing inhomogeneity of a certain absorption and volume can be approximately mimicked by a small totally absorbing object of a so-called Equivalent Black Volume (Equivalence Relation). This concept can be useful to design realistic inhomogeneous phantoms using a set of black objects with different volumes. Further, it permits to grade physiological or pathological changes on a reproducible scale of equivalent black volumes, thus facilitating the performance assessment of clinical instruments. We have also provided a plot to derive the Equivalent Black Volume yielding the same effect of a realistic absorption object.

Paper Details

Date Published: 28 February 2013
PDF: 8 pages
Proc. SPIE 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V, 85830C (28 February 2013); doi: 10.1117/12.2003665
Show Author Affiliations
Antonio Pifferi, Politecnico di Milano (Italy)
Fabrizio Martelli, Univ. degli Studi di Firenze (Italy)
Davide Contini, Politecnico di Milano (Italy)
Lorenzo Spinelli, Consiglio Nazionale delle Ricerche (Italy)
Alessandro Torricelli, Politecnico di Milano (Italy)
Heidrun Wabnitz, Physikalisch-Technische Bundesanstalt (Germany)
Rainer Macdonald, Physikalisch-Technische Bundesanstalt (Germany)
Angelo Sassaroli, Tufts Univ. (United States)
Giovanni Zaccanti, Univ. degli Studi di Firenze (Italy)


Published in SPIE Proceedings Vol. 8583:
Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V
Robert J. Nordstrom, Editor(s)

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