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Proceedings Paper

Inhibitory efficacy of the quantified prunellae spica extract on H22 tumor bearing mice
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Paper Abstract

Hepatocarcinoma, a malignant cancer, threaten human life badly. It is a current issue to seek the effective natural remedy from plant to treat cancer due to the resistence of the advanced hepatocarcinoma to chemotherapy. In this report, we assessed the antitumor activity of a prunellae spica aqueous extract (PSE) in vitro and in vivo. PSE was quantified by HPLC and UV. MTT assay showed that PSE did not effectively inhibit the growth of H22 cells. The in vivo anti-tumor activity was assessed by using the mice bearing H22 tumor. In vivo studies showed the higher antitumor efficacy of PSE without significant side effect assessed by the reduced tumor weight, and the extended survival time of the mice bearing H22 solid and ascites tumor. Collectively, PSE is a promising Chinese medicinal herb for treating hepatocarcinoma.

Paper Details

Date Published: 22 February 2013
PDF: 7 pages
Proc. SPIE 8582, Biophotonics and Immune Responses VIII, 85820S (22 February 2013); doi: 10.1117/12.2002844
Show Author Affiliations
Zhi-ping Wang, Guangdong Pharmaceutical Univ. (China)
Tong-sheng Chen, South China Normal Univ. (China)

Published in SPIE Proceedings Vol. 8582:
Biophotonics and Immune Responses VIII
Wei R. Chen, Editor(s)

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