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Proceedings Paper

Characterization of ovarian tissue using polarization-sensitive optical coherence tomography
Author(s): Tianheng Wang; Yi Yang; Xiaohong Wang; Melinda Sanders; Molly Brewer; Quing Zhu
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Paper Abstract

We characterized ovarian tissue by using polarization-sensitive optical coherence tomography (PS-OCT). Phase retardation changing rate along with optical scattering coefficient and phase retardation were extracted from 33 ex vivo human ovaries from 18 patients. By using phase retardation changing rate as a classifier, we could achieve 71% sensitivity and 100% specificity. Combining those three parameters together, we could achieve 100% sensitivity and 100% specificity. These initial results showed that the quantitative analysis of PS-OCT could be a useful tool to characterize normal and malignant ovarian tissue.

Paper Details

Date Published: 20 March 2013
PDF: 5 pages
Proc. SPIE 8571, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII, 857124 (20 March 2013); doi: 10.1117/12.2001515
Show Author Affiliations
Tianheng Wang, Univ. of Connecticut (United States)
Yi Yang, Univ. of Connecticut (United States)
Xiaohong Wang, Univ. of Connecticut Health Ctr. (United States)
Melinda Sanders, Univ. of Connecticut Health Ctr. (United States)
Molly Brewer, Univ. of Connecticut (United States)
Univ. of Connecticut Health Ctr. (United States)
Quing Zhu, Univ. of Connecticut (United States)


Published in SPIE Proceedings Vol. 8571:
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII
James G. Fujimoto; Joseph A. Izatt; Valery V. Tuchin, Editor(s)

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