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Proceedings Paper

Experimental investigation on region-based diffuse optical tomography
Author(s): Linhui Wu; Xi Yi; Wei Zhang; Jiao Li; Xin Wang; Limin Zhang; Huijuan Zhao; Feng Gao
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Paper Abstract

A region-based approach of image reconstruction using the finite element method is developed for diffuse optical tomography (DOT). The method is based on the framework of the pixel-based DOT methodology and on an assumption that different anatomical regions have their respective sets of the homogeneous optical properties distributions. With this hypothesis, the region-based DOT solution greatly improves the ill-posedness of the inverse problem by reducing the number of unknowns to be reconstructed. The experimental validation of the methodology is performed on a solid phantom employing a multi-channel DOT system of lock-in photon-counting mode, as well as compared with the traditional pixel-based reconstruction results, demonstrate that the proposed DOT methodology presents a promising tool of in vivo reconstructing background optical structures with the aid of anatomical a priori.

Paper Details

Date Published: 25 March 2013
PDF: 8 pages
Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85782T (25 March 2013); doi: 10.1117/12.2001044
Show Author Affiliations
Linhui Wu, Tianjin Univ. (China)
Xi Yi, Tianjin Univ. (China)
Wei Zhang, Tianjin Univ. (China)
Jiao Li, Tianjin Univ. (China)
Xin Wang, Tianjin Univ. (China)
Limin Zhang, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)
Huijuan Zhao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)
Feng Gao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)


Published in SPIE Proceedings Vol. 8578:
Optical Tomography and Spectroscopy of Tissue X
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca, Editor(s)

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