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Proceedings Paper

Color-matched esophagus phantom for fluorescent imaging
Author(s): Chenying Yang; Vivian Hou; Leonard Y. Nelson; Eric J. Seibel
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Paper Abstract

We developed a stable, reproducible three-dimensional optical phantom for the evaluation of a wide-field endoscopic molecular imaging system. This phantom mimicked a human esophagus structure with flexibility to demonstrate body movements. At the same time, realistic visual appearance and diffuse spectral reflectance properties of the tissue were simulated by a color matching methodology. A photostable dye-in-polymer technology was applied to represent biomarker probed “hot-spot” locations. Furthermore, fluorescent target quantification of the phantom was demonstrated using a 1.2mm ultrathin scanning fiber endoscope with concurrent fluorescence-reflectance imaging.

Paper Details

Date Published: 28 February 2013
PDF: 16 pages
Proc. SPIE 8583, Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V, 85830F (28 February 2013); doi: 10.1117/12.2000834
Show Author Affiliations
Chenying Yang, Univ. of Washington (United States)
Vivian Hou, Univ. of Washington (United States)
Leonard Y. Nelson, Univ. of Washington (United States)
Eric J. Seibel, Univ. of Washington (United States)


Published in SPIE Proceedings Vol. 8583:
Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue V
Robert J. Nordstrom, Editor(s)

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