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Proceedings Paper

The ellipsoid parametric description for the shape-based image reconstruction algorithm of diffuse optical tomography
Author(s): Yuan Wang; Linhui Wu; Mengyu Jia; Lingling Liu; Huijuan Zhao; Feng Gao
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Paper Abstract

As a new non-invasive medical imaging technology, diffuse optical tomography (DOT) has received considerable attention that can provide vast quantities of functional information of tissues. The reconstruction problem of DOT is highly ill-posed, meaning that a small error in the measurement data can bring about drastic errors of the reconstruction optical properties. In this paper, the shape-based image reconstruction algorithm of DOT is proposed for reducing the ill-poseness under the assumption that the optical properties of target region distribute uniformly. Since some human organs and tumors can be simplified as an ellipsoid, in this paper, the shape of the inhomogeneity is described as an ellipsoid. In the forward problem, the boundary element method (BEM) is implemented to solve the continuous wave diffusion equation (DE). By the use of the ellipsoid parametric method, the description of the shape, location and optical properties of the inhomogeneity, and the value of the background could be realized with only a small number of parameters. In the inverse calculation, a Levenberg-Marquardt algorithm with line searching is implemented to solve the underlying nonlinear least-squares problem. Simulation results show that the algorithm developed in this paper is effective in reducing the ill-poseness and robust to the noise.

Paper Details

Date Published: 25 March 2013
PDF: 9 pages
Proc. SPIE 8578, Optical Tomography and Spectroscopy of Tissue X, 85782R (25 March 2013); doi: 10.1117/12.2000813
Show Author Affiliations
Yuan Wang, Tianjin Univ. (China)
Linhui Wu, Tianjin Univ. (China)
Mengyu Jia, Tianjin Univ. (China)
Lingling Liu, Tianjin Univ. (China)
Huijuan Zhao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)
Feng Gao, Tianjin Univ. (China)
Tianjin Key Lab. of Biomedical Detecting Techniques and Instruments (China)


Published in SPIE Proceedings Vol. 8578:
Optical Tomography and Spectroscopy of Tissue X
Bruce J. Tromberg; Arjun G. Yodh; Eva Marie Sevick-Muraca, Editor(s)

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