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Proceedings Paper

Resting state brain networks and their implications in neurodegenerative disease
Author(s): William Seunghyun Sohn; Kwangsun Yoo; Jinho Kim; Yong Jeong
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Paper Abstract

Neurons are the basic units of the brain, and form network by connecting via synapses. So far, there have been limited ways to measure the brain networks. Recently, various imaging modalities are widely used for this purpose. In this paper, brain network mapping using resting state fMRI will be introduced with several applications including neurodegenerative disease such as Alzheimer’s disease, frontotemporal lobar degeneration and Parkinson’s disease. The resting functional connectivity using intrinsic functional connectivity in mouse is useful since we can take advantage of perturbation or stimulation of certain nodes of the network. The study of brain connectivity will open a new era in understanding of brain and diseases thus will be an essential foundation for future research.

Paper Details

Date Published: 24 October 2012
PDF: 10 pages
Proc. SPIE 8548, Nanosystems in Engineering and Medicine, 85483Z (24 October 2012); doi: 10.1117/12.2000254
Show Author Affiliations
William Seunghyun Sohn, KAIST (Korea, Republic of)
Kwangsun Yoo, KAIST (Korea, Republic of)
Jinho Kim, KAIST (Korea, Republic of)
Yong Jeong, KAIST (Korea, Republic of)


Published in SPIE Proceedings Vol. 8548:
Nanosystems in Engineering and Medicine
Sang H. Choi; Jin-Ho Choy; Uhn Lee; Vijay K. Varadan, Editor(s)

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