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Proceedings Paper

In vivo treatment of proliferations in the vitreous body with a holmium: YAG laser
Author(s): Stephan Schruender; Michael Foerster; Norbert Mueller-Stolzenburg; Steffen Sola; Isabella Schmitt; Gerhard J. Mueller
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Paper Abstract

A Holmium:YAG (Ho:YAG) laser assisted vitrectomy system has been developed. In vitro studies on porcine cadaver eyes were performed to determine optimal laser settings taking into account mechanical effects such as bubble formation and collapse and tissue displacements. Optimal laser settings were 60 - 80 mJ at a pulse length of 150 microsecond(s) . Measurements of induced shockwaves and associated effects led to the construction of a specially designed laser vitrectomy endoprobe that incorporates the distal end of a flexible fiber with 365 micrometers core diameter. Intraocular membranes and strands in the vitreous body of five rabbits were induced by injection of mouse fibroblasts. An additional five rabbits without alterations were treated as a control group. Cutting of membranes was possible and efficient at distances larger than 1.5 mm from the retina. Smaller distances partly led to injuries like retinal holes or ruptures that were induced by mechanical effects of the radiation.

Paper Details

Date Published: 12 January 1995
PDF: 3 pages
Proc. SPIE 2330, Lasers in Ophthalmology II, (12 January 1995); doi: 10.1117/12.199266
Show Author Affiliations
Stephan Schruender, Laser-Medizin-Zentrum GmbH (Germany)
Michael Foerster, Univ. Benjamin Franklin (Germany)
Norbert Mueller-Stolzenburg, Laser-Medizin-Zentrum GmbH (Germany)
Steffen Sola, Univ. Benjamin Franklin (Germany)
Isabella Schmitt, Laser-Medizin-Zentrum GmbH (Germany)
Gerhard J. Mueller, Laser-Medizin-Zentrum GmbH (Germany)


Published in SPIE Proceedings Vol. 2330:
Lasers in Ophthalmology II
Rosario Brancato; Adolf Friedrich Fercher; Pascal O. Rol; A. S. Melamed, Editor(s)

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