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Proceedings Paper

Corneal photoablation with a scanning beam of 213 nm radiation for alteration of refraction: a three-month follow up study of the rabbit
Author(s): Per G. Soederberg; Takaaki Matsui; Fabrice Manns; Jin-Hui Shen; Jean-Marie A. Parel; Jean-Marc Legeais M.D.; Michele Savoldelli; Isabelle Drubaix
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Paper Abstract

A scanning pulsed beam at 213 nm creates predictable correction of myopia but the surgical procedure with the presently used laser system is not yet sufficiently safe to proceed to human clinical trials. It was found that a 70% overlap of approximate active spot size provides a refractive change as predicted 1 week after ablation. There was a minimal transient increase of IOP shortly after the ablation. There was an immediate swelling of the cornea after the ablation that gradually decreased during the following 12 weeks. The corneal epithelium did not heal until around 4 - 7 weeks after the ablation. The epithelium stained with fluorescein late after the ablation. When considerable haze was seen it decreased towards the end of the 12 weeks of observation. Approximately 30% of ablated corneas showed vessel ingrowth at 12 weeks after ablation. The 213 nm beam was obtained by frequency quintupling of the output of a Nd-Yag laser. The beam was moved with an X-Y scanner.

Paper Details

Date Published: 12 January 1995
PDF: 6 pages
Proc. SPIE 2330, Lasers in Ophthalmology II, (12 January 1995); doi: 10.1117/12.199262
Show Author Affiliations
Per G. Soederberg, Univ. of Miami School of Medicine (Sweden)
Takaaki Matsui, Univ. of Miami School of Medicine (United States)
Fabrice Manns, Univ. of Miami School of Medicine (United States)
Jin-Hui Shen, Univ. of Miami School of Medicine (United States)
Jean-Marie A. Parel, Univ. of Miami School of Medicine (United States)
Jean-Marc Legeais M.D., Univ. de Paris (France)
Michele Savoldelli, Univ. de Paris (France)
Isabelle Drubaix, Univ. de Paris (France)

Published in SPIE Proceedings Vol. 2330:
Lasers in Ophthalmology II
Rosario Brancato; Adolf Friedrich Fercher; Pascal O. Rol; A. S. Melamed, Editor(s)

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