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Proceedings Paper

New fluorinated photosensitizers based on tetrakis(hydroxyphenyl) porphyrins
Author(s): Raymond Bonnett; S. Phinda Songca
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Paper Abstract

The potential advantages of fluorinated porphyrin photosensitizers are outlined. The syntheses of fluorinated analogues of sensitizers which are known to be active in vivo are described with particular reference to compounds of the tetrakis(hydroxyphenyl)porphyrin series. Three new fluorinated (hydroxyphenyl)porphyrins are prepared [5,10,15,20-tetrakis(2-fluoro-3- hydroxyphenyl)porphyrin; 5,10,15,20-tetrakis(2,4-difluoro-3-hydroxyphenyl)porphyrin; and 5,10,15,20-tetrakis(3,5-difluoro-4-hydroxyphenyl)porphyrin], and some of their relevant properties are described.

Paper Details

Date Published: 12 January 1995
PDF: 5 pages
Proc. SPIE 2325, Photodynamic Therapy of Cancer II, (12 January 1995); doi: 10.1117/12.199138
Show Author Affiliations
Raymond Bonnett, Queen Mary and Westfield College (United Kingdom)
S. Phinda Songca, Queen Mary and Westfield College (United Kingdom)

Published in SPIE Proceedings Vol. 2325:
Photodynamic Therapy of Cancer II
Daniel Brault; Giulio Jori; Johan Moan; Benjamin Ehrenberg, Editor(s)

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