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Proceedings Paper

Clinical measurements of tissue optical properties in the esophagus
Author(s): Roland Bays; Georges A. Wagnieres; D. Robert; Jerome C. Mizeret; Daniel Braichotte; Hubert van den Bergh; Jean-Francois Savary; Philippe Monnier
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Paper Abstract

A noninvasive probe has been devised and clinically used to perform in vivo measurements of the optical properties of the esophageal wall. The absorption coefficient and the effective scattering coefficient are determined from the observation of the spatial distribution of the diffuse reflectance at the tissue surface. Results, obtained at 514 and 630 nm, i.e. wavelengths of interest in photodynamic therapy with actual clinically used photosensitizers are summarized. An efficient and easily-built isotropic microprobe is also presented which is suitable to measure in situ the radiant energy fluence rate distribution in tissue.

Paper Details

Date Published: 4 January 1995
PDF: 7 pages
Proc. SPIE 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging, (4 January 1995); doi: 10.1117/12.198741
Show Author Affiliations
Roland Bays, Ecole Polytechnique Federale de Lausanne (Switzerland)
Georges A. Wagnieres, Massachusetts General Hospital (Switzerland)
D. Robert, Ecole Polytechnique Federale de Lausanne (Switzerland)
Jerome C. Mizeret, Ecole Polytechnique Federale de Lausanne (Switzerland)
Daniel Braichotte, Ecole Polytechnique Federale de Lausanne (Switzerland)
Hubert van den Bergh, Ecole Polytechnique Federale de Lausanne (Switzerland)
Jean-Francois Savary, CHUV Hospital (Switzerland)
Philippe Monnier, CHUV Hospital (Switzerland)


Published in SPIE Proceedings Vol. 2324:
Optical Biopsy and Fluorescence Spectroscopy and Imaging

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