Share Email Print
cover

Proceedings Paper

Noninvasive tissue fluorescence study of a fluorescent dye (calcein) on intraperitoneal glucose administration
Author(s): Jean-Marie Devoisselle; Serge R. Mordon; Sylvie Soulie-Begu
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

The diagnostic exploitation of fluorescence spectroscopy and imaging has been largely used in experimental and clinical oncology. Only a few studies concern the ability of these techniques to study the in vivo behavior of fluorescent drugs or dyes. We have proposed recently a spectroscopic and imaging method to monitor pH in living tissues using pH-sensitive dyes. The tumor pH was depressed by previous glucose injection. We describe in this study the effect of glucose injection on the pharmacokinetic behavior of a fluorescent dye (calcein) by noninvasive fluorescence spectroscopy.

Paper Details

Date Published: 4 January 1995
PDF: 8 pages
Proc. SPIE 2324, Optical Biopsy and Fluorescence Spectroscopy and Imaging, (4 January 1995); doi: 10.1117/12.198714
Show Author Affiliations
Jean-Marie Devoisselle, Univ. de Montpellier I (France)
Serge R. Mordon, INSERM (France)
Sylvie Soulie-Begu, Univ. de Montpellier I (France)


Published in SPIE Proceedings Vol. 2324:
Optical Biopsy and Fluorescence Spectroscopy and Imaging
Rinaldo Cubeddu; Renato Marchesini; Serge R. Mordon; Katarina Svanberg; Herbert H. Rinneberg; Georges A. Wagnieres, Editor(s)

© SPIE. Terms of Use
Back to Top