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Proceedings Paper

Tomsk Cardiology Center program on lasers in cardiovascular: first results
Author(s): Eugeni P. Gordov; Rostislav S. Karpov; Victor A. Dudko; Vladimir M. Shipulin M.D.
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Paper Abstract

Recent progress in biomedical optics resulted in increased activity in this area at a number of different centers. Reported are the first results of the program directed to incorporate at Tomsk Cardiology Center experience gained in Tomsk optical profile research institutions in areas of light-matter interaction, high resolution spectroscopy, laser physics and relevant software and their usage in cardiac therapy, surgery, and diagnostics. To coordinate research work in this direction the special unit-laboratory of laser medicine is organized at the Center. Laboratory activity goes in the following directions: study of spectral properties of vessel walls in norm and atherosclerosis, comparative study of different wavelength laser radiation action on normal and atherosclerotically damaged tissues, novel approach to intravascular imaging, and usage of high sensitive laser spectroscopy for early diagnosis of cardiac diseases. The spectroscopic study of AP and normal tissue is aimed at understanding of differences in internal energy structures and ways of energy migration which are of critical importance for reaching selective laser action on normal and deceased tissues. To compare thermal, mechanical, and photo-chemical variations of tissues caused by laser radiation the XeCl excimer laser with Raman shifting cell and Nd:YAG laser with second, third, and fourth harmonic converters are employed. Fine influence of pulse duration, intensity, and repetition rates on AP removal is considered in laboratory experiments with vessel samples. Preliminary results on theoretical consideration for determination of spectroscopically detectable markers of some cardiac diseases are reported as well.

Paper Details

Date Published: 23 December 1994
PDF: 4 pages
Proc. SPIE 2327, Medical Applications of Lasers II, (23 December 1994); doi: 10.1117/12.197582
Show Author Affiliations
Eugeni P. Gordov, Institute of Atmospheric Optics (Russia)
Rostislav S. Karpov, Institute of Cardiology (Russia)
Victor A. Dudko, Institute of Cardiology (Russia)
Vladimir M. Shipulin M.D., Institute of Cardiology (Russia)

Published in SPIE Proceedings Vol. 2327:
Medical Applications of Lasers II
Stephen G. Bown; J. Escourrou; Frank Frank; Herbert J. Geschwind M.D.; Guilhem Godlewski M.D.; Frederic Laffitte; Hans H. Scherer M.D., Editor(s)

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