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Proceedings Paper

Spectral and photochemical parameters which define the higher efficacy of laser phototherapy in hyperbilirubinemia in newborns
Author(s): Vasili A. Mostovnikov; Galina R. Mostovnikova; Vitali Yu Plavski
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Paper Abstract

It is shown that the efficacy of phototherapy of neonatal hyperbilirubinemia is considerably increased with substitution of traditional lamp sources by the argon laser light. The spectral range of the laser (476.5 - 514.5 nm) corresponds to low-frequency slope of bilirubin absorption spectrum. This rises quantum yield of lumirubin formation which is known for its high rate of excretion. The fact can be explained by the form of absorption spectrum of bilirubin which is the sum of two spectra of weakly bound chromophores, the spectrum of chromophore responsible for lumirubin production being shifted to lower frequencies. The second cause of higher efficacy of laser phototherapy with wavelength span 476.5 ... 514.5 is the less shielding effect of hemoglobin.

Paper Details

Date Published: 2 January 1995
PDF: 4 pages
Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); doi: 10.1117/12.197489
Show Author Affiliations
Vasili A. Mostovnikov, Institute of Physics (Belarus)
Galina R. Mostovnikova, Institute of Physics (Belarus)
Vitali Yu Plavski, Institute of Physics (Belarus)

Published in SPIE Proceedings Vol. 2370:
5th International Conference on Laser Applications in Life Sciences
Pavel A. Apanasevich; Nikolai I. Koroteev; Sergei G. Kruglik; Victor N. Zadkov, Editor(s)

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