Share Email Print
cover

Proceedings Paper

Molecular mechanisms of DNA photocleavage by laser
Author(s): Sergei Khrapunov; Anatolii Dragan; Boris Pavlik; Nikolai Zubrilin
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

The laser action on chromosomes of living cells in the presence and absence of exogenous chromophore (ethydium bromide) was studied. Also investigated was the possible role of the endogenous chromophores, such as riboflavin, in this mutagenic action. We show that riboflavin induces DNA strand cleavages at N2-laser irradiation. First the nonlinear mechanism of DNA cleavage by laser in the presence of riboflavin has been proven. Quantum yield of DNA strand cleavages by laser in the presence of riboflavin has been calculated.

Paper Details

Date Published: 2 January 1995
PDF: 4 pages
Proc. SPIE 2370, 5th International Conference on Laser Applications in Life Sciences, (2 January 1995); doi: 10.1117/12.197488
Show Author Affiliations
Sergei Khrapunov, Kiev Univ. (Ukraine)
Anatolii Dragan, Kiev Univ. (Ukraine)
Boris Pavlik, Institute of Physics (Ukraine)
Nikolai Zubrilin, Institute of Physics (Ukraine)


Published in SPIE Proceedings Vol. 2370:
5th International Conference on Laser Applications in Life Sciences

© SPIE. Terms of Use
Back to Top