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Proceedings Paper

Improved SPECT via cone-beam collimation, the expectation maximization algorithm, and accurate attenuation correction
Author(s): A. Welch; Stephen E. D. Webb; M. Flower
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Paper Abstract

The Expectation Maximisation (EM) algorithm for computing the Maximum Likelihood image has been applied to both simulated and experimental cone-beam SPECT projection data. Reconstructions of simulated data show the superiority of the EM algorithm over a convolution and backprojection (CBP) algorithm with respect to image uniformity across the field of view and tolerance to noise. Phantom studies demonstrate the need for an accurate attenuation correction routine. A method of correcting for photon attenuation has been applied to the EM algorithm assuming the object to be a uniform attenuator. A method of extending this to allow for non uniform photon attenuation is also proposed.

Paper Details

Date Published: 1 July 1990
PDF: 11 pages
Proc. SPIE 1231, Medical Imaging IV: Image Formation, (1 July 1990); doi: 10.1117/12.18810
Show Author Affiliations
A. Welch, Institute of Cancer Research/Royal Marsden Hospital (United Kingdom)
Stephen E. D. Webb, Institute of Cancer Research/Royal Marsden Hospital (United Kingdom)
M. Flower, Institute of Cancer Research/Royal Marsden Hospital (United Kingdom)

Published in SPIE Proceedings Vol. 1231:
Medical Imaging IV: Image Formation
Roger H. Schneider, Editor(s)

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