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Proceedings Paper

P-31 magnetic resonance spectroscopy and near-infrared spectroscopy provide unique quantitative data for evaluation of exercising muscles
Author(s): Jane H. Park; Daniel Golwyn; Nancy J. Olsen; John H. Newman; Alvin C. Powers; Beverly C. Davis; Kara Rader; Britton Chance
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Paper Abstract

P-31 magnetic resonance spectroscopy (MRS) and near-infra spectroscopy (NIRS) have been used to characterize the dynamic aspects of human muscle contraction. P-31 MRS is a non- invasive method for measuring ATP, phosphocreatine (PCr), and pH in exercising muscles and thereby provides information regarding oxidative and glycolytic capacities for generating high energy phosphate compounds. NIRS evaluates kinetic changes in oxygen levels in muscles during exercise and recovery. These two methods provide unique quantitative data for studies of normal muscle contraction and for more complex investigations of muscle diseases. Non-invasive MRS and NIRS examinations are readily repeatable and yield important data for longitudinal patient evaluation and therapeutic management.

Paper Details

Date Published: 14 September 1994
PDF: 12 pages
Proc. SPIE 2275, Advanced Microwave and Millimeter-Wave Detectors, (14 September 1994); doi: 10.1117/12.186722
Show Author Affiliations
Jane H. Park, Vanderbilt Univ. Medical School (United States)
Daniel Golwyn, Vanderbilt Univ. Medical School (United States)
Nancy J. Olsen, Vanderbilt Univ. Medical School (United States)
John H. Newman, Vanderbilt Univ. Medical School (United States)
Alvin C. Powers, Vanderbilt Univ. Medical School (United States)
Beverly C. Davis, Vanderbilt Univ. Medical School (United States)
Kara Rader, Vanderbilt Univ. Medical School (United States)
Britton Chance, Univ. of Pennsylvania (United States)


Published in SPIE Proceedings Vol. 2275:
Advanced Microwave and Millimeter-Wave Detectors
Satish S. Udpa; Hsiu C. Han, Editor(s)

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