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Proceedings Paper

Effect of clenbuterol on cardiopulmonary parameters and intramuscular blood flow by laser Doppler flowmetry in anesthetized ponies
Author(s): Yong Hoon Lee; Kathleen Williamson Clarke; Hatim I. K. Alibhai
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Paper Abstract

The cardiopulmonary affects and the affects on muscular microperfusion of the beta adrenergic agonist, clenbuterol (0.8 mcg/kg intravenously), were investigated in dorsally recumbent anesthetized ponies. Muscle microcirculation was measured by laser Doppler flowmetry, utilizing fine optical fiber probes. Other measurements included heart rate, cardiac output, arterial blood pressure, and arterial blood gas tensions. Clenbuterol injection caused a regular, but transitory rise in muscle microcirculation, an increase in heart rate, and cardiac output and a decrease in mean arterial blood pressure. Clenbuterol did appear to prevent the continuing fall in arterial blood oxygen tensions seen in the treatment groups, but had only minimal affects in reversing the hypoxia already present.

Paper Details

Date Published: 7 September 1994
PDF: 5 pages
Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); doi: 10.1117/12.184948
Show Author Affiliations
Yong Hoon Lee, Univ. of London Royal Veterinary College (United Kingdom)
Kathleen Williamson Clarke, Univ. of London Royal Veterinary College (United Kingdom)
Hatim I. K. Alibhai, Univ. of London Royal Veterinary College (United Kingdom)


Published in SPIE Proceedings Vol. 2128:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV
R. Rox Anderson; R. Rox Anderson, Editor(s)

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