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Proceedings Paper

Endoscopic diode-laser applications in airway surgery
Author(s): Michail M. Pankratov; Zhi Wang; Elie E. Rebeiz; Donald F. Perrault; Stanley M. Shapshay; Lyon L. Gleich
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Paper Abstract

A technique was developed to secure small mucosal grafts onto the airway wound with fibrin/albumin tissue adhesive mixed with ICG dye and irradiated with a 810 nm diode laser. An in vitro study of the tensile strength produced strong mucosal soldering which was adequate to fix grafts in place. In vivo studies showed that wounds with mucosal grafts were completely covered by regenerated squamous cells in 1 week and by ciliated epithelium in 2 weeks. Excellent healing was observed at 6 and 14 days postoperatively and the histology at 28 days found normal epithelium over the vocal cord lesion. This soldering technique is a less traumatic treatment for patients with extensive lesions of the larynx of various origin. Diode laser soldering with ICG-doped fibrin tissue adhesive was evaluated in tracheal anastomosis as a substitute for absorbable sutures. In vitro studies demonstrated strong anastomoses with minimal tissue damage. In vivo animal study showed that these anastomoses had less fibrosis and tissue damage than control animals repaired with sutures only.

Paper Details

Date Published: 7 September 1994
PDF: 8 pages
Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); doi: 10.1117/12.184910
Show Author Affiliations
Michail M. Pankratov, New England Medical Ctr./Tufts Univ. School of Medicine (United States)
Zhi Wang, New England Medical Ctr./Tufts Univ. School of Medicine (United States)
Elie E. Rebeiz, New England Medical Ctr./Tufts Univ. (United States)
Donald F. Perrault, New England Medical Ctr./Tufts Univ. School of Medicine (United States)
Stanley M. Shapshay, New England Medical Ctr./Tufts Univ. School of Medicine (United States)
Lyon L. Gleich, New York Eye and Ear Infirmary (United States)


Published in SPIE Proceedings Vol. 2128:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV
R. Rox Anderson; R. Rox Anderson, Editor(s)

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