Share Email Print
cover

Proceedings Paper

Holmium:YAG laser effects on articular cartilage metabolism: in vitro
Author(s): R. Lane Smith; L. Montgomery; G. Fanton; M. Dillingham; D. J. Schurman
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

We report effects of applying variable doses of Holmium:YAG laser energy to bovine articular cartilage in vitro. The response of the cartilage to the Holmium:YAG laser energy was determined by quantification of cell proliferation and extracellular matrix glycosaminoglycan synthesis. This study demonstrates that articular cartilage cell metabolism was maintained at a normal level following treatment of cartilage at a dose of 0.6 joules/pulse. The laser energy was applied at 10 Hz for 10 seconds at 1 mm distance from the cartilage. Under these conditions and at a dose of 0.6 joules/pulse, the total energy density was calculated to be 240 joules/cm2, assuming minimal loss of energy due to water absorption. Energy levels grater than 0.8 joules/pulse corresponding to calculated energy densities greater than 320 joules/cm2 proved harmful to cartilage. Our data demonstrate that low levels of Holmium:YAG laser energy can be applied to articular cartilage under conditions that maintain and/or stimulate cell metabolism.

Paper Details

Date Published: 7 September 1994
PDF: 5 pages
Proc. SPIE 2128, Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV, (7 September 1994); doi: 10.1117/12.184892
Show Author Affiliations
R. Lane Smith, Stanford Univ. School of Medicine (United States)
L. Montgomery, Stanford Univ. School of Medicine (United States)
G. Fanton, Stanford Univ. School of Medicine (United States)
M. Dillingham, Stanford Univ. School of Medicine (United States)
D. J. Schurman, Stanford Univ. School of Medicine (United States)


Published in SPIE Proceedings Vol. 2128:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems IV
R. Rox Anderson; R. Rox Anderson, Editor(s)

© SPIE. Terms of Use
Back to Top