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Proceedings Paper

Dielectro-deformational spectroscopy of erythrocytes
Author(s): Vadim L. Kononenko
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Paper Abstract

The theory of dielectro-deformational spectroscopy (DDS) of erythrocytes is considered. DDS utilizes the deformation of a cell by high frequency (HF) electric field registered by optical diffractometry or by microphotometering for the monitoring of mechanical and (or) electric properties of erythrocyte. The general dynamic equation of dielectro-deformations of erythrocyte is presented and used to consider the registering of (1) the stationary elongation of a cell as a function of HF amplitude; (2) the elongation-relaxation curves for a step-like variation of HF amplitude; and (3) the oscillatory elongation of a cell due to harmonic modulation of HF amplitude. The determination of erythrocyte electric properties from the frequency dispersion of its dielectro-deformational response is considered also. The connection of the registered curves is elucidated with three main groups of erythrocyte's parameters: mechanical (shear modulus and viscosity of a membrane), geometric (surface area and volume), and electric (conductivities and dielectric constants inside and outside of a cell).

Paper Details

Date Published: 21 July 1994
PDF: 12 pages
Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); doi: 10.1117/12.180804
Show Author Affiliations
Vadim L. Kononenko, N.N. Semenov Institute of Chemical Physics (Russia)


Published in SPIE Proceedings Vol. 2136:
Biochemical Diagnostic Instrumentation
Robert F. Bonner; Gerald E. Cohn; Thomas M. Laue; Alexander V. Priezzhev, Editor(s)

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