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Proceedings Paper

Ultrasensitive intracavity molecular spectroscopy for diagnostic applications
Author(s): Eugeni P. Gordov; Michail M. Makogon; Iren V. Sukhodolo
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Paper Abstract

Intracavity laser spectroscopy (ILS) presents itself as a highly effective technique that allows one to detect the change of light signal from absorbing molecules at a level of radiation quantum noise. Thus high sensitivity of ICLS allows one to determine the absorbing molecules concentrations in gases and liquids in the range between 10-6 to 10-10. The potential of ICLS technique employment for establishing interrelations between small changes in the breathed air caused by diseases in the early stage, as well as a mass screening of patients with diseases of the liver and kidneys by acetone and urea detection in breathed air, and with heart diseases by measurement of CO2 concentration is discussed. Usage of gas, dye and solid-state lasers for such measurements is analyzed, optimum spectral ranges are presented.

Paper Details

Date Published: 21 July 1994
PDF: 4 pages
Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); doi: 10.1117/12.180797
Show Author Affiliations
Eugeni P. Gordov, Institute of Atmospheric Optics (Russia)
Michail M. Makogon, Institute of Atmospheric Optics (Russia)
Iren V. Sukhodolo, Siberian Medical Univ. (Russia)


Published in SPIE Proceedings Vol. 2136:
Biochemical Diagnostic Instrumentation
Robert F. Bonner; Gerald E. Cohn; Thomas M. Laue; Alexander V. Priezzhev, Editor(s)

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