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Proceedings Paper

Modern equilibrium ultracentrifugation: applications of automated interferometry
Author(s): David A. Yphantis; Jeffrey W. Lary
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Paper Abstract

The development of automated interferometry for the ultracentrifuge is presented briefly, along with a short description of our current `real-time' acquisition system for equilibrium studies. Use of this system and of the associated data analyses techniques for both conventional and short solution column experiments of various types are discusses with emphasis on the application of nonlinear least squares fitting procedures. A brief summary is presented of the use of these approaches to detect and measure heterogeneity of various types.

Paper Details

Date Published: 21 July 1994
PDF: 12 pages
Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); doi: 10.1117/12.180787
Show Author Affiliations
David A. Yphantis, Univ. of Connecticut and Univ. of Crete (United States)
Jeffrey W. Lary, Univ. of Connecticut (United States)


Published in SPIE Proceedings Vol. 2136:
Biochemical Diagnostic Instrumentation
Robert F. Bonner; Gerald E. Cohn; Thomas M. Laue; Alexander V. Priezzhev, Editor(s)

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