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Proceedings Paper

Diffractometric control in erythrocyte damage low-energy laser treatment
Author(s): Igor Z. Nemtsev
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Paper Abstract

Laser cytodiffractometry which allows to analyse the shape of erythrocytes being in the nontensed conditions was used to objectivise the results of the technique application in treatment. Quantitative parameters of the physiological solution motion in cytodiffractometer pipeline are giv~n in this paper. The reasons of erythrocyte cytoplasm spiral mode motion are discussed. The oscillations of diffraction minimum formed by the spinning erythrocytes are explained. The results of the experiment with an air bubble, attached to the cuvette walls, are represented. The investigations of erythrocytes concentration increase and the possibility of the erythrocytes magnetic moment analysis as well as its clinical significance are discussed. It is proved that the diffraction ellipse eccentricity reflect the erythrocyte membrane deformation not by shear stress, as the inventors of the device said, but by intracellular osmotic pressure (increased as a cause of an acute decease). The investigation of the wattertunneling through the erythrocyte membrane kinetics is proposed. The results of the low energy laser treatment fundamental mechanismes investigations are given. Detecting of threshold dose of treating physical influence on blood is given. The information about the measuring the amplitude-frequency characteristics of erythrocytes is represented. The fundamental investigations, using this device, are proposed.

Paper Details

Date Published: 21 July 1994
PDF: 8 pages
Proc. SPIE 2136, Biochemical Diagnostic Instrumentation, (21 July 1994); doi: 10.1117/12.180779
Show Author Affiliations
Igor Z. Nemtsev, Sklifosovsky Scientific Research Institute for Emergency Medicine (United States)


Published in SPIE Proceedings Vol. 2136:
Biochemical Diagnostic Instrumentation
Robert F. Bonner; Gerald E. Cohn; Thomas M. Laue; Alexander V. Priezzhev, Editor(s)

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