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Proceedings Paper

Nd3+ doped glass fluorescent-tip fiber optical probes for quantitative fluence rate dosimetry in biological tissue
Author(s): Lothar D. Lilge; Glenn N. Merberg; Ralph Sebastian DaCosta; Brian C. Wilson
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Paper Abstract

Improved fluorescent-tip fiber optical fluence-rate detectors with solid state fluorophores are presented. In these optical fibers a small end-section of the core is doped with rare earth ions (Nd3+, Er3+) or is replaced by a fluorescent crystal such as ruby. Thus, this section of the core emits fluorescent light when irradiated with the treatment light to be measured. Angular isotropy and spectral response characteristics of these light detectors are presented. An advantage of solid state probes is their narrow fluorescence emission band and large Stokes shift, allowing also for fluorescence measurements of endogenous or exogenous fluorophores in the tissue. The possibility of simultaneous quantitative fluence-rate and photosensitizer dosimetry by interstitially implanted fiber optic detectors is discussed.

Paper Details

Date Published: 28 July 1994
PDF: 10 pages
Proc. SPIE 2131, Biomedical Fiber Optic Instrumentation, (28 July 1994); doi: 10.1117/12.180707
Show Author Affiliations
Lothar D. Lilge, Hamilton Regional Cancer Ctr. (Canada)
Glenn N. Merberg, Food & Drug Administration (United States)
Ralph Sebastian DaCosta, Ontario Cancer Institute/Princess Margaret Hospital (Canada)
Brian C. Wilson, Ontario Cancer Institute/Princess Margaret Hospital (Canada)

Published in SPIE Proceedings Vol. 2131:
Biomedical Fiber Optic Instrumentation
James A. Harrington; David M. Harris; Abraham Katzir; Fred P. Milanovich, Editor(s)

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