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Proceedings Paper

Dynamics of the binding and change of photosensitizers of phthalocyanine row concentration in malignant tumors: experimental results
Author(s): Victor B. Loschenov; Anna I. Volkova; A. I. Volegov; T. A. Kramarenko; Sergey S. Kharnas; Anna M. Posypanova; Alexander A. Stratonnikov; Eugeny A. Lukyanets; P. V. Poleshkin; Nadezgda L. Torshina
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Paper Abstract

The results of investigations of photosensitizers distribution, accumulation and outputting in the process of photodynamic therapy on the model of Erlikh carcinoma in the experiment are adduced. Phthalocyanines of Al, differing in technology of synthesis and content of sulfa groups, have been used. The character of photosensitizer binding has been determined by the change of its spectral characteristics after binding with albumin in vitro and by analysis of fine structure of fluorescence spectra in vivo.

Paper Details

Date Published: 28 June 1994
PDF: 3 pages
Proc. SPIE 2100, Cell and Biotissue Optics: Applications in Laser Diagnostics and Therapy, (28 June 1994); doi: 10.1117/12.179014
Show Author Affiliations
Victor B. Loschenov, General Physics Institute (Russia)
Anna I. Volkova, General Physics Institute (Russia)
A. I. Volegov, General Physics Institute (Russia)
T. A. Kramarenko, General Physics Institute (Russia)
Sergey S. Kharnas, General Physics Institute (Russia)
Anna M. Posypanova, General Physics Institute (Russia)
Alexander A. Stratonnikov, General Physics Institute (Russia)
Eugeny A. Lukyanets, General Physics Institute (Russia)
P. V. Poleshkin, General Physics Institute (Russia)
Nadezgda L. Torshina, General Physics Institute (Russia)

Published in SPIE Proceedings Vol. 2100:
Cell and Biotissue Optics: Applications in Laser Diagnostics and Therapy
Valery V. Tuchin, Editor(s)

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