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Proceedings Paper

Phthalocyanines as second generation photosensitizers for the photodynamic therapy of cancer: fluorescence and absorption spectroscopy
Author(s): L. V. Zhorina; Elena B. Chernyaeva; A. V. Agronskaya; Maria G. Galpern
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Paper Abstract

We studied the pH-dependence of the fluorescence and absorption spectra of concentrated solutions of tetrasulphonated aluminum phthalocyanine (AlPcS4)--the potent photosensitizer for the photodynamic therapy of cancer. The possible use of AlPcS4 as the pH-sensitive fluorescent probe for local pH measurements is discussed. By means of numerical Alentsev's procedure the individual spectral components of the fluorescence spectrum main band were resolved.

Paper Details

Date Published: 28 June 1994
PDF: 8 pages
Proc. SPIE 2100, Cell and Biotissue Optics: Applications in Laser Diagnostics and Therapy, (28 June 1994); doi: 10.1117/12.178996
Show Author Affiliations
L. V. Zhorina, Moscow State Univ. (Russia)
Elena B. Chernyaeva, Moscow State Univ. (Russia)
A. V. Agronskaya, Moscow State Univ. (Russia)
Maria G. Galpern, Institute of Organic Intermediates and Dyes (Russia)

Published in SPIE Proceedings Vol. 2100:
Cell and Biotissue Optics: Applications in Laser Diagnostics and Therapy
Valery V. Tuchin, Editor(s)

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