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Proceedings Paper

Biocolonizable keratoprosthesis with a microporous fluorocarbon skirt: a two-year study
Author(s): Jean-Marc Legeais; Gilles Renard; Jean-Marie A. Parel; Michele Savoldelli; Yves Pouliquen
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Paper Abstract

Most complications of keratoprosthesis (KPro) occur at the tissue-to-implant interface. The ideal prosthesis would eliminate this interface by having the tissue actually grown into the support material forming the haptic. We present a 2-year clinical human study of a novel biocolonizable KPro on 24 eyes of 24 patients. To promote tissue stability, a 9 mm (Phi) skirt made of a new microporous fluorocarbon was used. The optical core or the KPro optic was made of a medical grade polymethylmetacrylate (PMMA) commonly used world-wide to fabricate intraocular lenses. The optic was 5 mm in diameter and 2.67 mm long. The average follow-up was 14 months. Mean corrected visual acuity was 20/100. Anatomic failures occurred in 5 cases in the first year (1 lens dislocation, 1 endophthalmitis, 3 extrusions). These preliminary results appear encouraging. However, we did not eliminate all the complications with this biocompatible inert microporous polymer. Intensive research in mechanical, chemical, and surface biocompatibility is required to develop a true artificial cornea.

Paper Details

Date Published: 23 June 1994
PDF: 6 pages
Proc. SPIE 2126, Ophthalmic Technologies IV, (23 June 1994); doi: 10.1117/12.178572
Show Author Affiliations
Jean-Marc Legeais, Hopital de l'Hotel-Dieu/Univ. de Paris (France)
Gilles Renard, Hopital de l'Hotel-Dieu/Univ. de Paris (France)
Jean-Marie A. Parel, Hopital de l'Hotel-Dieu/U de Paris and Bascom Palmer Eye Institute/Univ. of Miami School of Medicine (United States)
Michele Savoldelli, Hopital de l'Hotel-Dieu/Univ. de Paris (France)
Yves Pouliquen, Hopital de l'Hotel-Dieu/Univ. de Paris (France)


Published in SPIE Proceedings Vol. 2126:
Ophthalmic Technologies IV
Jean-Marie A. Parel; Qiushi Ren, Editor(s)

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