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Proceedings Paper

Angioscopic and angiographic characteristics of de novo and restenotic lesions following successful coronary rotational atherectomy and balloon angioplasty
Author(s): Youssef G. Chami; Theodore A. Bass; Barbara J. Kircher; Christopher J. White; Suresh P. Jain; Paul S. Gilmore; Donald A. Conetta
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Paper Abstract

We used coronary angiography and angioscopy prior and following balloon angioplasty (PTCA) and high speed rotational atherectomy (PTCRA) in order to 1) Assess morphological and surface luminal characteristics of de novo (DN) and restenotic (RS) lesions, 2) Compare surface luminal characteristics following PTCA and PTCRA. 3) Investigate whether lesion morphology helped predict response to therapy; 39 lesions were studied in 38 patients undergoing elective coronary intervention. Angiographic and angioscopic variables were compared by Pearson Chi-square. Angiography pre-intervention was not different in DN and RS lesion. On post intervention angiography, presence of intimal dissection was significantly higher in the PTCA group (p < 0.001). On preintervention angioscopy smooth white lesions differentiated RS from DN lesions (yellow colored lesion) (p < 0.01) while color difference persisted post intervention; smoothness and absence of plaque fracture were device related as noted in the atherectomy group (p < 0001). No other lesion variables noted prc.4ntervention hipcd dfffcrentiatz DN from RS lesions or predict response to catheter therapy. We conclude: 1) angioscopy is superior to angiography in assessing surface luminal characteristics; 2) smooth white lesions characterized RS lesions pre—intervention and color difference persisted after intervention. 3) surface luminal characteristics were very different following PTCRA vs. PTCA with a) angiographically less intimal dissection and b) angioscopically smoother lumen with less plaque fracture following PTCRA.

Paper Details

Date Published: 26 May 1994
PDF: 3 pages
Proc. SPIE 2132, Clinical Applications of Modern Imaging Technology II, (26 May 1994); doi: 10.1117/12.176557
Show Author Affiliations
Youssef G. Chami, Univ. of Florida Health Science Ctr. (United States)
Theodore A. Bass, Univ. of Florida Health Science Ctr. (United States)
Barbara J. Kircher, Univ. of Florida Health Science Ctr. (United States)
Christopher J. White, Alton Ochsner Medical Institutions (United Kingdom)
Suresh P. Jain, Alton Ochsner Medical Institutions (United States)
Paul S. Gilmore, Univ. of Florida Health Science Ctr. (United States)
Donald A. Conetta, Univ. of Florida Health Science Ctr. (United States)


Published in SPIE Proceedings Vol. 2132:
Clinical Applications of Modern Imaging Technology II
Leonard J. Cerullo; Kenneth S. Heiferman; Hong Liu; Halina Podbielska; Abund Ottokar Wist; Lucia J. Zamorano, Editor(s)

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