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Proceedings Paper

Simulation of ablation and thermal damage in CO2 laser-irradiated tissue
Author(s): Miron Gerstmann; A. M. Sagi; Ariella Avidor; Abraham Katzir; Solange Akselrod
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Paper Abstract

A previously described numerical model which calculates heat transfer in biological tissue exposed to Co2 laser irradiation was adapted and applied to predict the amount of ablated tissue and peripheral damage under high power pulsed irradiation. The main object of this work is to search for the irradiation parameters which minimize damage. Simulations of pulsed irradiation were carried out employing rabbit brain tissue thermal constants and varying the following irradiation parameters: pulse duration, repetition rate of the pulse train and beam profile. A Gaussian profile with a beam radius of 1mm was employed over a series of l5OmJ single pulses differing in duration. An optimal value of lms for pulse length was obtained. No improvement was observed at lower durations. Next, the pulse length was kept constant and the effect of the repetition rate of a pulse train was investigated. The damaged volume was shown to increase with repetition rate, however, at very high repetition rates damage decreased to the minimal values observed for the low range of repetition rates. Similar procedures carried out using a rectangular beam profile showed that lateral damage reduced to widths of a few microns with pulse lengths shorter than ims. In addition, ablation thresholds and ablation rates were calculated for both profiles. The theoretical values obtained agree with previous experimental results.

Paper Details

Date Published: 1 June 1990
PDF: 14 pages
Proc. SPIE 1202, Laser-Tissue Interaction, (1 June 1990); doi: 10.1117/12.17639
Show Author Affiliations
Miron Gerstmann, Tel Aviv Univ. (Israel)
A. M. Sagi, Tel Aviv Univ. (Israel)
Ariella Avidor, Tel Aviv Univ. (Israel)
Abraham Katzir, Tel Aviv Univ. (Israel)
Solange Akselrod, Tel Aviv Univ. (Israel)

Published in SPIE Proceedings Vol. 1202:
Laser-Tissue Interaction
Steven L. Jacques, Editor(s)

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