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Proceedings Paper

Ablation of atheroma by laser energy: a comparative study of the efficacy of different temporal rates of energy deposition
Author(s): Donald J. Ramsay; Philip J. Walker; Nicola G. Dadswell; James May; James A. Piper; Christine Wacher
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Paper Abstract

Laser angioplasty continues to attract interest as a potential method for treating atherosclerotic arterial disease. Current efforts are aimed at finding the most effective combination of laser and delivery system. High energy pulsed ultraviolet or infrared lasers demonstrate good photoablative properties but there remain practical difficulties with the optical fibre delivery. Continuous wave lasers are widely used in conjunction with "hot-tip" fibres for thermal ablation but their direct (optical) ablation efficiency is low, causing significant surrounding thermal damage in soft tissue. While considerable attention has been directed previously at the ablative effects for different laser wavelengths, little systematic study has been made of the efficacy for different temporal rates of energy deposition. We have compared the efficacy for tissue ablation in cadaveric human aorta of three different laser systems with similar wavelengths in the visible (green) but different temporal rates of energy deposition. The laser sources were the continuous wave argon ion laser (514.5 nm), the high pulse energy, frequency doubled Nd:YAG laser (532 nm) and the copper vapour laser. The copper vapour laser is a high repetition rate, high average power, pulsed laser emitting in the green (511 nm) and yellow (578 nm) which has temporal characteristics intermediate between those of the Nd:YAG laser and the argon ion laser, and has the potential to be effective both for direct optical ablation and hot-tip thermal ablation.

Paper Details

Date Published: 1 June 1990
PDF: 11 pages
Proc. SPIE 1202, Laser-Tissue Interaction, (1 June 1990); doi: 10.1117/12.17621
Show Author Affiliations
Donald J. Ramsay, Macquarie Univ. (Australia)
Philip J. Walker, Univ. of Sydney (Australia)
Nicola G. Dadswell, Macquarie Univ. (Australia)
James May, Univ. of Sydney (Australia)
James A. Piper, Macquarie Univ. (Australia)
Christine Wacher, Univ. of Sydney (Australia)

Published in SPIE Proceedings Vol. 1202:
Laser-Tissue Interaction
Steven L. Jacques, Editor(s)

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