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Proceedings Paper

Noninvasive spectroscopic diagnosis of superficial ocular lesions and corneal infections
Author(s): Judith R. Mourant; Irving J. Bigio; D. C. Gritz; Randolph D. Glickman; Tamara M. Johnson; Tsutomu Shimada; K. Story-Held
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Paper Abstract

The potential of a rapid noninvasive diagnostic system to detect tissue abnormalities on the surface of the eye has been investigated. The optical scatter signal from lesions and normal areas on the conjunctival sclera of the human eye were measured in vivo. It is possible to distinguish nonpigmented pingueculas from other lesions. The ability of the system to detect malignancies could not be tested because none of the measured and biopsied lesions were malignant. Optical scatter and fluorescence spectra of bacterial and fungal suspensions, and corneal irritations were also collected. Both scattering and fluorescence show potential for diagnosing corneal infections.

Paper Details

Date Published: 19 May 1994
PDF: 10 pages
Proc. SPIE 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases, (19 May 1994); doi: 10.1117/12.176002
Show Author Affiliations
Judith R. Mourant, Los Alamos National Lab. (United States)
Irving J. Bigio, Los Alamos National Lab. (United States)
D. C. Gritz, Univ. of Texas Health Science Ctr./San Antonio (United States)
Randolph D. Glickman, Univ. of Texas Health Science Ctr./San Antonio (United States)
Tamara M. Johnson, Los Alamos National Lab. (United States)
Tsutomu Shimada, Los Alamos National Lab. (United States)
K. Story-Held, Univ. of Texas Health Science Ctr./San Antonio (United States)


Published in SPIE Proceedings Vol. 2135:
Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases
Robert R. Alfano, Editor(s)

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