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Proceedings Paper

Charge-coupled device and neural-network-based instrument for the noninvasive determination of tissue optical properties in vivo
Author(s): Thomas J. Farrell; Michael S. Patterson; Joseph E. Hayward; Brian C. Wilson; Elsa R. Beck
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Paper Abstract

We describe an instrument which will permit simultaneous collection of radial resolved reflectance over the spectral range 600-1000 nm and a neural network algorithm which permits real- time analysis of the data. The in vivo performance of the instrument is presently under investigation. Data will be presented illustrating the performance of the instrument over the useful optical spectrum for certain tissues of interest. In addition the derived tissue concentrations of photosensitizers will be compared with those obtained using chemical extraction techniques on excised tissue samples.

Paper Details

Date Published: 19 May 1994
PDF: 12 pages
Proc. SPIE 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases, (19 May 1994); doi: 10.1117/12.175987
Show Author Affiliations
Thomas J. Farrell, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
Michael S. Patterson, Hamilton Regional Cancer Ctr., McMaster Univ., and Ontario Laser and Lightwave Research Ctr. (Canada)
Joseph E. Hayward, Hamilton Regional Cancer Ctr. and McMaster Univ. (Canada)
Brian C. Wilson, Ontario Laser and Lightwave Research Ctr., Ontario Cancer Institute, and Univ. of Toronto (Canada)
Elsa R. Beck, Henry Ford Hospital (United States)


Published in SPIE Proceedings Vol. 2135:
Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases
Robert R. Alfano, Editor(s)

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