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Proceedings Paper

Pathological studies using laserthermia with Nd:YAG laser
Author(s): Naoto Mamiya; Hiroshi Tsunekawa; M. Sugihara; Masataka Shinoda; Yoko Sasano; Chein Chang Chen; Kenji Ina; Kimitomo Morise; Yoshinori Watanabe; Tsutomu Tsunekawa; Norio Daikuzono
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Paper Abstract

In 198k we developed a method of hyperthermia using Nd:YAG laser (laser thermia) a system for transmitting continuous low power energy (2 W) through an artificial sapphire interstitial probe for local hyperthermia (43-0.5°C). Our experimental and clinical evidence indicated that this method is safe and effective. The process of tumor destruction induced by laser thermia is, however, poorly understood. We performed in vivo histopathological studies and obtained the following results; 1) At the tissue level, the initial change after laser thermia was the damage of tumor feeding vessels. 2) At the cell level, immediately after laser thermia the mitochondria in the intracellular organella were completely destroyed.

Paper Details

Date Published: 1 July 1990
PDF: 7 pages
Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); doi: 10.1117/12.17595
Show Author Affiliations
Naoto Mamiya, Meitetsu Hospital (Japan)
Hiroshi Tsunekawa, Meitetsu Hospital (Japan)
M. Sugihara, Meitetsu Hospital (Japan)
Masataka Shinoda, Meitetsu Hospital (Japan)
Yoko Sasano, Meitetsu Hospital (Japan)
Chein Chang Chen, Meitetsu Hospital (Japan)
Kenji Ina, Nagoya Univ. School of Medicine (Japan)
Kimitomo Morise, Nagoya Univ. School of Medicine (Japan)
Yoshinori Watanabe, Nagoya Laser Medical Lab. (Japan)
Tsutomu Tsunekawa, Nagoya Laser Medical Lab. (Japan)
Norio Daikuzono, Surgical Laser Technologies Co., Ltd. (Japan)


Published in SPIE Proceedings Vol. 1201:
Optical Fibers in Medicine V
Abraham Katzir, Editor(s)

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