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Proceedings Paper

Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd:YAG laser: early clinical results
Author(s): Christopher J. White; Stephen R. Ramee; Juan E. Mesa; Larry H. Hollier; Joseph P. Murgo; Michael Aita; Gene Samson; Maureen A. Godfrey
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Paper Abstract

We performed a clinical trial to evaluate the safety and efficacy of a unique lensed-fiber delivery system with a pulsed Neodymium-yttrium aluminum garnet (Nd-YAG) laser in patients with atherosclerotic peripheral vascular disease. The lensed-fiber consists of a spherical silica lens, 1 .5 mm in diameter, mounted at the distal tip of a 300 im silica optical fiber. The Nd-YAG laser is pulsed at 10 Hz, and we delivered 0.5 J/pulse with a pulse duration of 100 msecs in 2- to 5-second bursts. Successful recanalization of stenoses or occlusions was obtained in 9 of 10 patients and was manifested by improvement in blood flow as measured angiographically and with ankle-brachial blood pressure index improvement (> 0. 15). There were no arterial perforations or dissections associated with the laser angioplasty. All successfully recanalized patients required adjunctive balloon angioplasty to obtain a satisfactory reduction in luminal diameter stenosis of the treated artery. We conclude that this unique delivery system and the pulsed Nd-YAG laser are a safe and effect method of recanalizing arterial stenoses not amenable to conventional balloon angioplasty alone.

Paper Details

Date Published: 1 July 1990
PDF: 5 pages
Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); doi: 10.1117/12.17538
Show Author Affiliations
Christopher J. White, Ochsner Medical Institutions (United States)
Stephen R. Ramee, Ochsner Medical Institutions (United States)
Juan E. Mesa, Ochsner Medical Institutions (United States)
Larry H. Hollier, Ochsner Medical Institutions (United States)
Joseph P. Murgo, Ochsner Medical Institutions (United States)
Michael Aita, Advanced Cardiovascular Systems, Inc. (United States)
Gene Samson, Advanced Cardiovascular Systems, Inc. (United States)
Maureen A. Godfrey, Advanced Cardiovascular Systems, Inc. (United States)

Published in SPIE Proceedings Vol. 1201:
Optical Fibers in Medicine V
Abraham Katzir, Editor(s)

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