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Proceedings Paper

Temporal changes in the canine prostate after transurethral prostatectomy with a cylindrically diffusing fiber
Author(s): Douglas M. Cromeens; Roger E. Price; Douglas E. Johnson
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Paper Abstract

Visual laser ablation of the prostate was performed on 8 mongrel dogs employing a cylindrically diffusing fiber delivery system and a 1.06 neodymium:YAG laser. Each dog received 15,000 J of laser energy delivered to the prostate in one continuous dose of 25 W for 10 min. Gross and histopathologic examination of serial sections of the prostate was performed at intervals from 2 hours to 7 weeks postoperatively. Grossly, a spherical zone of destruction averaging 2.8 cm in diameter was present in all dogs. Histopathologic changes in the prostate consisted of acute coagulative necrosis with interstitial edema at 2 hours, becoming hemorrhagic at 24 hours. A prominent circular area of acute coagulative necrosis with extensive areas of liquefaction and hemorrhage was presented at 4 days. Early re- epithelialization of the resulting cavity was present at 3 weeks with nearly complete resolution 7 weeks postoperatively. We believe that, because of the simplified fiber placement and complete lack of postoperative complications in this small group of dogs, the cylindrically diffusing fiber could offer significant advantage over side fire-style fibers for transurethral prostatectomies.

Paper Details

Date Published: 2 May 1994
PDF: 4 pages
Proc. SPIE 2129, Lasers in Urology, (2 May 1994); doi: 10.1117/12.175020
Show Author Affiliations
Douglas M. Cromeens, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Roger E. Price, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Douglas E. Johnson, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)


Published in SPIE Proceedings Vol. 2129:
Lasers in Urology
Graham M. Watson; Rudolf W. Steiner; Douglas E. Johnson, Editor(s)

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