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Proceedings Paper

Interstitial laser prostatectomy
Author(s): Douglas E. Johnson; Douglas M. Cromeens; Roger E. Price
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Paper Abstract

Interstitial laser coagulation of the canine prostate using the Sharplan interstitial thermal therapy fiber (Model 25432) was performed in 9 adult dogs and the subsequent gross and histopathologic changes occurring in the prostate were studied at intervals ranging from 1 hour to 5 weeks. A large well-demarcated area of acute coagulative necrosis developed around each fiber tract which in turn was surrounded by a prominent narrow zone of marked tissue disruption and an outer zone of hemorrhage. Liquefaction developed within the coagulative areas within 24 hours and by 4 days, each prostatic lobe contained an irregular cavity which became lined by normal-appearing transitional epithelium and that by 5 weeks, communicated with the prostatic urethra. These changes, similar to those reported following transurethral visual laser ablation of the prostate, suggest that interstitial laser thermal therapy may provide an alternative means for treating selected patients suffering from prostatic enlargement.

Paper Details

Date Published: 2 May 1994
PDF: 5 pages
Proc. SPIE 2129, Lasers in Urology, (2 May 1994); doi: 10.1117/12.175019
Show Author Affiliations
Douglas E. Johnson, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Douglas M. Cromeens, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)
Roger E. Price, Univ. of Texas M.D. Anderson Cancer Ctr. (United States)

Published in SPIE Proceedings Vol. 2129:
Lasers in Urology
Graham M. Watson; Rudolf W. Steiner; Douglas E. Johnson, Editor(s)

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