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Proceedings Paper

Combined MRI-EEG techniques for correlation of anatomy and function in human somatosensory cortex
Author(s): James P. Boyle; Edward F. Kelly
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Paper Abstract

Recent advances in high-resolution EEG imaging methods have made it advantageous to decrease inter-electrode distance to approximately 1 - 2 cm. To take full advantage of this increased recording density, it has become imperative to consider inter-subject anatomical variability and even intra-subject anatomical asymmetry. The present study used anatomical information from MRI to augment functional data obtained through EEG. Specifically, acrylic helmets made for each subject and normally used during EEG were utilized to orient NMR sample tubes filled with a marker medium (H2O(DOT)Cu2SO4) radially from the scalp at selected EEG recording sites during MRI. Using the software package AVS, the MRI data could then be volumetrically 3-D rendered, 3-D isosurface rendered, or arbitrarily sliced. The tubes appeared in the 3-D renderings as pointers from recording sites to underlying cortical anatomy. Our task was simplified by our focus on a limited area of the cortex. The renderings provide subject-specific anatomical templates for mapping of EEG topographic patterns and clearly reveal individual variations of cortical surface topography that are usually unaccounted for in EEG analysis.

Paper Details

Date Published: 1 May 1994
PDF: 8 pages
Proc. SPIE 2168, Medical Imaging 1994: Physiology and Function from Multidimensional Images, (1 May 1994); doi: 10.1117/12.174397
Show Author Affiliations
James P. Boyle, Univ. of North Carolina/Chapel Hill (United States)
Edward F. Kelly, Univ. of North Carolina/Chapel Hill (United States)

Published in SPIE Proceedings Vol. 2168:
Medical Imaging 1994: Physiology and Function from Multidimensional Images
Eric A. Hoffman; Raj S. Acharya, Editor(s)

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