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Proceedings Paper

Scan timing considerations in indicator dilution analysis of dynamic CT image sequences
Author(s): Erik Leo Ritman
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Paper Abstract

Dynamic computed tomography (CT) provides the advantages of sampling in many regions within an organ where a sampling catheter could not be introduced and eliminates superposition. However, dynamic CT is generally slow. An important aspect of the indicator dilution curve generation is the sampling frequency and sample duration. The indicator dilution curves generated with a CT scanner must behave like the `conventional' indicators. The contrast agent passes sequentially through the heart chambers and in doing so the duration of the bolus increases and the peak opacification of the bolus diminishes. The pattern of progressive dispersal of the dilution curve, somewhat in proportion to the duration of the curve's transit along the circulation, conveys something about the structure-to-function relationship of the circulation through which the indicator passes. The standard deviation to mean transit time relationship in the aortic root appears to be along a different regression line than does that relationship in the myocardium.

Paper Details

Date Published: 1 May 1994
PDF: 11 pages
Proc. SPIE 2168, Medical Imaging 1994: Physiology and Function from Multidimensional Images, (1 May 1994); doi: 10.1117/12.174395
Show Author Affiliations
Erik Leo Ritman, Mayo Clinic and Foundation (United States)

Published in SPIE Proceedings Vol. 2168:
Medical Imaging 1994: Physiology and Function from Multidimensional Images
Eric A. Hoffman; Raj S. Acharya, Editor(s)

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