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Proceedings Paper

Morphological and functional effects of induced laser retinal fibrosis
Author(s): Harry Zwick; Steven T. Schuschereba; Donald A. Gagliano; M. Silverman; David J. Lund; Scottie B. Reynolds; Bruce E. Stuck
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Paper Abstract

Human laser accident exposure cases may involve severe macula retinal injury resulting in long term visual acuity and spatial vision deficit. In order to investigate this problem, we have chosen to model the effects of such long term exposure in the monkey retina for parafoveal Q- switched exposure produced at two parafoveal exposure sites. Our results suggest significant loss of retinal function in and adjacent to the scar region. Recovery occurs in regions with less scar formation, the foveal region, although long term changes in foveal receptor mechanisms are apparent even after 1 year post-exposure, they do not correlate completely with recent human investigations of severe accidental exposure nor with brain enzyme analysis in our monkey model.

Paper Details

Date Published: 15 February 1994
PDF: 14 pages
Proc. SPIE 2079, Laser Applications in Ophthalmology, (15 February 1994); doi: 10.1117/12.168742
Show Author Affiliations
Harry Zwick, U.S. Army Medical Research Detachment (United States)
Steven T. Schuschereba, U.S. Army Medical Research Detachment (United States)
Donald A. Gagliano, U.S. Army Medical Research Detachment (United States)
M. Silverman, Washington Univ. (United States)
David J. Lund, U.S. Army Medical Research Detachment (United States)
Scottie B. Reynolds, U.S. Army Medical Research Detachment (United States)
Bruce E. Stuck, U.S. Army Medical Research Detachment (United States)


Published in SPIE Proceedings Vol. 2079:
Laser Applications in Ophthalmology
Shlomo Timor Melamed, Editor(s)

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